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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
10.5 DPC

22 matching records from 22 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Mesp2  mesoderm posterior 2   (Synonyms: bHLHc6)
Results  Reference
1J:90513 Bussen M, Petry M, Schuster-Gossler K, Leitges M, Gossler A, Kispert A, The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes Dev. 2004 May 15;18(10):1209-21
1*J:239985 Casaca A, Novoa A, Mallo M, Hoxb6 can interfere with somitogenesis in the posterior embryo through a mechanism independent of its rib-promoting activity. Development. 2016 Feb 01;143(3):437-48
1J:178365 Cunningham TJ, Zhao X, Duester G, Uncoupling of retinoic acid signaling from tailbud development before termination of body axis extension. Genesis. 2011 Oct;49(10):776-83
1J:154114 Ferjentsik Z, Hayashi S, Dale JK, Bessho Y, Herreman A, De Strooper B, del Monte G, de la Pompa JL, Maroto M, Notch is a critical component of the mouse somitogenesis oscillator and is essential for the formation of the somites. PLoS Genet. 2009 Sep;5(9):e1000662
1*J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*J:66901 Johnson J, Rhee J, Parsons SM, Brown D, Olson EN, Rawls A, The anterior/posterior polarity of somites is disrupted in paraxis-deficient mice. Dev Biol. 2001 Jan 1;229(1):176-87
1*J:93008 Kokubu C, Heinzmann U, Kokubu T, Sakai N, Kubota T, Kawai M, Wahl MB, Galceran J, Grosschedl R, Ozono K, Imai K, Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis. Development. 2004 Nov;131(21):5469-80
1J:151888 Mead TJ, Yutzey KE, Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14420-5
1J:119678 Morimoto M, Kiso M, Sasaki N, Saga Y, Cooperative Mesp activity is required for normal somitogenesis along the anterior-posterior axis. Dev Biol. 2006 Dec 15;300(2):687-98
1*J:123846 Morimoto M, Sasaki N, Oginuma M, Kiso M, Igarashi K, Aizaki K, Kanno J, Saga Y, The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite. Development. 2007 Apr;134(8):1561-9
1J:110233 Nakajima Y, Morimoto M, Takahashi Y, Koseki H, Saga Y, Identification of Epha4 enhancer required for segmental expression and the regulation by Mesp2. Development. 2006 Jul;133(13):2517-25
1J:346126 Pappas MP, Kawakami H, Corcoran D, Chen KQ, Scott EP, Wong J, Gearhart MD, Nishinakamura R, Nakagawa Y, Kawakami Y, Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm. Development. 2024 Mar 1;151(5)
1J:42014 Saga Y, Hata N, Koseki H, Taketo MM, Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev. 1997 Jul 15;11(14):1827-39
1*J:88955 Schwabe GC, Trepczik B, Suring K, Brieske N, Tucker AS, Sharpe PT, Minami Y, Mundlos S, Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndrome. Dev Dyn. 2004 Feb;229(2):400-10
1J:142110 Shifley ET, Cole SE, Lunatic fringe protein processing by proprotein convertases may contribute to the short protein half-life in the segmentation clock. Biochim Biophys Acta. 2008 Dec;1783(12):2384-90
1J:131837 Shifley ET, Vanhorn KM, Perez-Balaguer A, Franklin JD, Weinstein M, Cole SE, Oscillatory lunatic fringe activity is crucial for segmentation of the anterior but not posterior skeleton. Development. 2008 Mar;135(5):899-908
1*J:125818 Teppner I, Becker S, de Angelis MH, Gossler A, Beckers J, Compartmentalised expression of Delta-like 1 in epithelial somites is required for the formation of intervertebral joints. BMC Dev Biol. 2007;7:68
1*J:82167 White PH, Farkas DR, McFadden EE, Chapman DL, Defective somite patterning in mouse embryos with reduced levels of Tbx6. Development. 2003 Apr;130(8):1681-90
1J:240090 Williams DR, Shifley ET, Braunreiter KM, Cole SE, Disruption of somitogenesis by a novel dominant allele of Lfng suggests important roles for protein processing and secretion. Development. 2016 Mar 01;143(5):822-30
1*J:208899 Williams DR, Shifley ET, Lather JD, Cole SE, Posterior skeletal development and the segmentation clock period are sensitive to Lfng dosage during somitogenesis. Dev Biol. 2014 Apr 15;388(2):159-69
1J:154781 Young T, Rowland JE, van de Ven C, Bialecka M, Novoa A, Carapuco M, van Nes J, de Graaff W, Duluc I, Freund JN, Beck F, Mallo M, Deschamps J, Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos. Dev Cell. 2009 Oct;17(4):516-26
1J:170604 Zhang Z, O'Rourke JR, McManus MT, Lewandoski M, Harfe BD, Sun X, The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning. Dev Biol. 2011 Mar 15;351(2):254-65

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory